Fenben is a medication commonly used to treat parasites and worms (roundworms, hookworms, whipworms and some tapeworms) in animals (commonly known as Pancur or Safe-Guard). It’s also being used by humans as part of the Joe Tippens Protocol. The Joe Tippens Protocol is an alternative cancer treatment that combines fenbendazole with curcumin and CBD.
The benzimidazole carbamate family of dewormers (I’m coining the term “fenben”) have been in use for over six decades, mostly as broad-spectrum anthelmintics, and they are very effective against roundworms. The benzimidazoles are also effective against tapeworms, and they work by disrupting microtubules.
But fenbendazole for humans has more than just the ability to kill parasites and worms; recent research has found that it can significantly inhibit tumor growth and may even be considered a possible cure for cancer. It’s not a stand-alone anticancer drug; it works best when combined with other treatments, including radiation, surgery, chemotherapy, berberine and sodium dichloroacetate (DCA).
The way in which fenben acts against cancer is different from that of the vinca alkaloids. It interacts with a site on tubulin that’s not affected by cyclin-dependent kinases (CDKs) or mitotic spindle checkpoint proteins. It prevents the phosphorylation of tubulin, which is required for the formation of microtubules. Tubulin is involved in a variety of essential cell functions, such as cell division and the transport of organelles and other molecules.
When fenbendazole binds with tubulin, it interrupts the assembly of the microtubules that are responsible for cell growth and division. This results in the disruption of the cell cycle and ultimately leads to cell death.
In laboratory tests, fenbendazole significantly reduced the size of human hepatocellular carcinoma tumors and significantly increased survival time in mice with large hepatocellular carcinoma tumors. The fenbendazole-induced apoptosis occurred through the induction of multiple pathways, including p21-mediated cell-cycle arrest.
Fenbendazole has also been shown to inhibit the growth of human melanoma, ovarian and prostate cancer cells in vitro. These effects were associated with the inhibition of the phosphorylation of tubulin, as well as the induction of multiple pathways that lead to cell death.
Another exciting finding in the research of fenben for humans is that this compound can reactivate the p53 genome in cancer cells. The p53 gene is the tumor suppressor that prevents cancer from developing, so it’s important to keep this gene active in the body to protect against malignancies.
There is still limited research on fenben for humans, but so far it’s looking promising. The medication is typically well tolerated and has not been reported to cause any serious side effects. However, you should always consult your doctor before beginning any new supplements or treatments. Regardless, the Joe Tippens Protocol is an alternative cancer therapy that could benefit anyone struggling with aggressive cancers or those who have already experienced recurrence. It’s definitely worth considering, and it might just be the key to a cancer-free life.